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RTI-120

維基百科,自由的百科全書
RTI-120
識別資訊
  • phenyl (1R,2S,3S,5S)-3-(4-methylphenyl)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate
CAS號146145-20-2
PubChem CID
ChemSpider
UNII
CompTox Dashboard英語CompTox Chemicals Dashboard (EPA)
化學資訊
化學式C22H25NO2
摩爾質量335.45 g·mol−1
3D模型(JSmol英語JSmol
  • CN1[C@@H]2C[C@H](C3=CC=C(C)C=C3)[C@H](C(OC4=CC=CC=C4)=O)[C@H]1CC2
  • InChI=1S/C22H25NO2/c1-15-8-10-16(11-9-15)19-14-17-12-13-20(23(17)2)21(19)22(24)25-18-6-4-3-5-7-18/h3-11,17,19-21H,12-14H2,1-2H3/t17-,19+,20+,21-/m0/s1
  • Key:HIQHQNWJRSNELD-KCLUMXDGSA-N

RTI-120是一種含氮有機化合物,開發代號:RTI-4229-120,分子式C22H25NO2,可用作多巴胺再攝取抑制劑,同時對去甲腎上腺素血清素的再攝取抑制作用較弱[1]

參考文獻

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  1. ^ Silverthorn ML, Dersch CM, Baumann MH, Cadet JL, Partilla JS, Rice KC, Carroll FI, Becketts KM, Brockington A, Rothman RB. Studies of the biogenic amine transporters. V. Demonstration of two binding sites for the cocaine analog [125I]RTI-55 associated with the 5-HT transporter in rat brain membranes. The Journal of Pharmacology and Experimental Therapeutics. April 1995, 273 (1): 213–22. PMID 7714769. 

外部連結

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