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RTI-120

维基百科,自由的百科全书
RTI-120
识别信息
  • phenyl (1R,2S,3S,5S)-3-(4-methylphenyl)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate
CAS号146145-20-2
PubChem CID
ChemSpider
UNII
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
化学信息
化学式C22H25NO2
摩尔质量335.45 g·mol−1
3D模型(JSmol英语JSmol
  • CN1[C@@H]2C[C@H](C3=CC=C(C)C=C3)[C@H](C(OC4=CC=CC=C4)=O)[C@H]1CC2
  • InChI=1S/C22H25NO2/c1-15-8-10-16(11-9-15)19-14-17-12-13-20(23(17)2)21(19)22(24)25-18-6-4-3-5-7-18/h3-11,17,19-21H,12-14H2,1-2H3/t17-,19+,20+,21-/m0/s1
  • Key:HIQHQNWJRSNELD-KCLUMXDGSA-N

RTI-120是一种含氮有机化合物,开发代号:RTI-4229-120,分子式C22H25NO2,可用作多巴胺再摄取抑制剂,同时对去甲肾上腺素血清素的再摄取抑制作用较弱[1]

参考文献

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  1. ^ Silverthorn ML, Dersch CM, Baumann MH, Cadet JL, Partilla JS, Rice KC, Carroll FI, Becketts KM, Brockington A, Rothman RB. Studies of the biogenic amine transporters. V. Demonstration of two binding sites for the cocaine analog [125I]RTI-55 associated with the 5-HT transporter in rat brain membranes. The Journal of Pharmacology and Experimental Therapeutics. April 1995, 273 (1): 213–22. PMID 7714769. 

外部链接

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