胆固醇侧链裂解酶
胆固醇侧链裂解酶（英语：Cholesterol side-chain cleavage enzyme，CYP11A1或P450scc，其中“scc”是“side-chain 侧链”“cleavage 裂解”的缩写）是一种将胆固醇转化为孕烯醇酮的线粒体酶。这是所有哺乳动物中由胆固醇生成各种甾类激素的第一步反应[7]。
P450scc 是细胞色素P450氧化酶超家族的一员（家族11亚家族A多肽1），基因名为 CYP11A1[8]。
另见
[编辑]参考文献
[编辑]- ^ 與胆固醇侧链裂解酶相關的疾病；在維基數據上查看/編輯參考.
- ^ 對胆固醇侧链裂解酶起作用的藥物；在維基數據上查看/編輯參考.
- ^ 3.0 3.1 3.2 GRCh38: Ensembl release 89: ENSG00000140459、ENSG00000288362 - Ensembl, May 2017
- ^ 4.0 4.1 4.2 GRCm38: Ensembl release 89: ENSMUSG00000032323 - Ensembl, May 2017
- ^ Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Hanukoglu I. Steroidogenic enzymes: structure, function, and role in regulation of steroid hormone biosynthesis. The Journal of Steroid Biochemistry and Molecular Biology. December 1992, 43 (8): 779–804. PMID 22217824. doi:10.1016/0960-0760(92)90307-5.
- ^ Entrez Gene: CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1.
延伸阅读
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