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系统基因组学

维基百科,自由的百科全书

系统基因组学泛指在系统发生学分析中运用基因组尺度的序列数据的研究方法[1][2]。随着2010年代下半高通量测序平台的飞速发展[3]以及简化测序策略[4]的开发,在较短时间内获得成百上千的基因座数据已经成许多生物研究领域的常规,而相应的系统发生分析工具的开发使研究者可以比对不同个体的整个或部分基因组[5],无需拘囿于单个或少数基因,从而更为准确客观地推断不同分类元或群落层级的生物演化历史。

参考资料

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  1. ^ Kumar S, Filipski AJ, Battistuzzi FU, Kosakovsky Pond SL, Tamura K. Statistics and truth in phylogenomics. Molecular Biology and Evolution. February 2012, 29 (2): 457–472. PMC 3258035可免费查阅. PMID 21873298. doi:10.1093/molbev/msr202. 
  2. ^ McKain, Michael R; Johnson, Matthew G; Uribe‐Convers, Simon; Eaton, Deren; Yang, Ya. Practical considerations for plant phylogenomics. Applications in Plant Sciences. 2018-04-02, 6 (3) [2025-01-28]. 
  3. ^ Barrett, Craig F.; Bacon, Christine D.; Antonelli, Alexandre; Cano, Ángela; Hofmann, Tobias. An introduction to plant phylogenomics with a focus on palms. Botanical Journal of the Linnean Society. 2016-10, 182 (2): 234–255. doi:10.1111/boj.12399 (英语). 
  4. ^ DaCosta, Jeffrey M.; Sorenson, Michael D. ddRAD-seq phylogenetics based on nucleotide, indel, and presence–absence polymorphisms: Analyses of two avian genera with contrasting histories. Molecular Phylogenetics and Evolution. 2016-01, 94: 122–135. doi:10.1016/j.ympev.2015.07.026. 
  5. ^ Pennisi E. Evolution. Building the tree of life, genome by genome. Science. June 2008, 320 (5884): 1716–1717. PMID 18583591. S2CID 206580993. doi:10.1126/science.320.5884.1716.